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Telomerase-Targeted Cancer Immunotherapy

12 Apr 2019

Abstract excerpt

Telomerase, an enzyme responsible for the synthesis of telomeres, is activated in many cancer cells and is involved in the maintenance of telomeres. The activity of telomerase allows cancer cells to replicate and proliferate in an uncontrolled manner, to infiltrate tissue, and to metastasize to distant organs. Studies to date have examined the mechanisms involved in the survival of cancer cells as targets for...

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PMID: 31013796
DOI: 10.3390/ijms20081823

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