Article
Genetic variants in ultraconserved elements and risk of breast cancer in Chinese population.
Breast cancer research and treatment - 1 Aug 2011
Shen Hao, Lu Cheng, Jiang Yue, Tang Jinhai, Chen Wei, Zhang Hanze, Zhang Qin, Wang Jianming, Liang Jie, Hu Zhibin, Shen Hongbing
Abstract excerpt
Ultraconserved elements (UCEs) are the most extreme representatives of conserved non-coding sequences. Recent studies have indicated that UCEs are not mutation cold regions and likely to be concerned with cancers, including breast cancer (BC). In this study, we first screened common single-nucleotide polymorphisms (SNPs) (minor allele frequency, MAF > 0.05) in Chinese population located in 481 UCEs sequences and...
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