Article
Analysis of allelic differential expression in the human genome using allele-specific serial analysis of gene expression tags.
Genome - 1 Feb 2011
Vidal Daniel Onofre, de Souza Jorge Estefano S, Pires Lilian Campos, Masotti Cibele, Salim Anna Christina Matos, Costa Maria Cristina Ferreira, Galante Pedro Alexandre Favoretto, de Souza Sandro José, Camargo Anamaria Aranha
Abstract excerpt
Recent reports have demonstrated that a significant proportion of human genes display allelic differential expression (ADE). ADE is associated with phenotypic variability and may contribute to complex genetic diseases. Here, we present a computational analysis of ADE using allele-specific serial analysis of gene expression (SAGE) tags representing 1295 human genes. We identified 472 genes for which unequal...
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