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Article

Effect of apolipoprotein ε4 allele on hippocampal and brain volume in intractable temporal lobe epilepsy.

Epilepsy & behavior : E&B - 1 May 2011

Busch Robyn M, Floden Darlene, Lineweaver Tara T, Chapin Jessica S, Unnwongse Kanjana, Wehner Tim, Diaz-Arrastia Ramon, Najm Imad M

Abstract excerpt

This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volumes in patients with medically intractable temporal lobe epilepsy (TLE). MRI-based volumetric analyses of the hippocampi, cerebral hemispheres, and whole brain were conducted in 59 patients with TLE (31 with left TLE, 28 with right TLE) with hippocampal sclerosis (HS). There were no differences in hippocampal,...

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Source

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Identifiers

PMID: 21317045
DOI: 10.1016/j.yebeh.2011.01.007
PMCID: PMC13198858

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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