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Article

Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences.

Analytical chemistry - 15 Dec 2011

Rowe Aaron A, Chuh Kelly N, Lubin Arica A, Miller Erin A, Cook Brett, Hollis Daniel, Plaxco Kevin W

Abstract excerpt

Electrochemical DNA (E-DNA) sensors, which are rapid, reagentless, and readily integrated into microelectronics and microfluidics, appear to be a promising alternative to optical methods for the detection of specific nucleic acid sequences. Keeping with this, a large number of distinct E-DNA architectures have been reported to date. Most, however, suffer from one or more drawbacks, including low signal gain (the...

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PMID: 21975121
DOI: 10.1021/ac202171x
PMCID: PMC3249395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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