Article
Impact of genotyping on outcome of prostatic biopsies: a multicenter prospective study.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Cornu Jean-Nicolas, Drouin Sarah, Cancel-Tassin Géraldine, Bigot Pierre, Azzouzi Abdel-Rahmène, Koutlidis Nicolas, Cormier Luc, Gaffory Cécile, Rouprêt Morgan, Sèbe Philippe, Bitker Marc-Olivier, Haab François, Cussenot Olivier
Abstract excerpt
Single nucleotide polymorphisms (SNPs) have been associated with prostate cancer (PCa) risk and tumor aggressiveness in retrospective studies. To assess the value of genotyping in a clinical setting, we evaluated the correlation between three genotypes (rs1447295 and rs6983267[8q24] and rs4054823[17p12]) and prostatic biopsy outcome prospectively in a French population of Caucasian men. Five hundred ninety-eight...
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