Article
Combination effect of cetuximab with radiation in colorectal cancer cells.
Tumori - 1 Jan 2000
Shin Hye Kyung, Kim Mi-Sook, Lee Jin Kyung, Lee Seung-Sook, Ji Young Hoon, Kim Jong-Il, Jeong Jae-Hoon
Abstract excerpt
AIMS AND BACKGROUND: Colorectal cancer (CRC) is one of the commonest malignant disorders and frequently associated with high expression of epidermal growth factor receptor (EGFR), resulting in advanced disease and a poor prognosis. In this study, we investigated the radiosensitizing effects of the selective EGFR inhibitor cetuximab in human CRC cell lines. METHODS: Four human CRC cell lines, CaCo-2, HCT-8, LoVo,...
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