Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2011

Chang Shun-Chiao, Pauls David L, Lange Christoph, Sasanfar Roksana, Santangelo Susan L

Abstract excerpt

Biological and positional evidence supports the involvement of the GAD1 and distal-less homeobox genes (DLXs) in the etiology of autism. We investigated 42 single nucleotide polymorphisms in these genes as risk factors for autism spectrum disorders (ASD) in a large family-based association study of 715 nuclear families. No single marker showed significant association after correction for multiple testing. A rare...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child Development Disorders, Pervasive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family

Share to Genes, Homeobox

Share to Glutamate Decarboxylase

Share to Haplotypes

Share to Homeodomain Proteins

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 21302352
DOI: 10.1002/ajmg.b.31148
PMCID: PMC3088769

Genes

GAD1
DLX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.PMID 21302352Read ↗

The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.Semantic proximity Read ↗

Analysis of four DLX homeobox genes in autistic probands.Semantic proximity Read ↗

Analysis of the autism chromosome 2 linkage region: GAD1 and other candidate genes.Semantic proximity Read ↗

Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene.Semantic proximity Read ↗

Lack of Association Between Polymorphisms in Dopa Decarboxylase and Dopamine Receptor-1 Genes With Childhood Autism in Chinese Han Population.Semantic proximity Read ↗

No evidence for IL1RAPL1 involvement in selected high-risk autism pedigrees from the AGRE data set.Semantic proximity Read ↗

Contribution of common and rare variants of the PTCHD1 gene to autism spectrum disorders and intellectual disability.Semantic proximity Read ↗

A population-based association study of glutamate decarboxylase 1 as a candidate gene for autism.Semantic proximity Read ↗

No association between common variants in glyoxalase 1 and autism spectrum disorders.Semantic proximity Read ↗

An SNP in an ultraconserved regulatory element affects Dlx5/Dlx6 regulation in the forebrain.Semantic proximity Read ↗

No association of polymorphisms in the CDK5, NDEL1, and LIS1 with autism in Chinese Han population.Semantic proximity Read ↗

Sequence variants of the DRD4 gene in autism: further evidence that rare DRD4 7R haplotypes are ADHD specific.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.