Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of four DLX homeobox genes in autistic probands.

BMC genetics - 2 Nov 2005

Hamilton Steven P, Woo Jonathan M, Carlson Elaine J, Ghanem Nöel, Ekker Marc, Rubenstein John L R

Abstract excerpt

BACKGROUND: Linkage studies in autism have identified susceptibility loci on chromosomes 2q and 7q, regions containing the DLX1/2 and DLX5/6 bigene clusters. The DLX genes encode homeodomain transcription factors that control craniofacial patterning and differentiation and survival of forebrain inhibitory neurons. We investigated the role that sequence variants in DLX genes play in autism by in-depth resequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Enhancer Elements, Genetic
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family Health

Share to Homeodomain Proteins

Share to Inheritance Patterns

Share to Pedigree

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 16266434
DOI: 10.1186/1471-2156-6-52
PMCID: PMC1310613

Genes

DLX5
DLX1
DLX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of four DLX homeobox genes in autistic probands.PMID 16266434Read ↗

The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.Semantic proximity Read ↗

Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.Semantic proximity Read ↗

Function and regulation of AUTS2, a gene implicated in autism and human evolution.Semantic proximity Read ↗

Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder.Semantic proximity Read ↗

Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene.Semantic proximity Read ↗

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.Semantic proximity Read ↗

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.Semantic proximity Read ↗

Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese population.Semantic proximity Read ↗

Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.Semantic proximity Read ↗

Association Between DLX4 Polymorphisms and Nonsyndromic Orofacial Clefts in a Chinese Han Population.Semantic proximity Read ↗

Heterogeneous association between engrailed-2 and autism in the CPEA network.Semantic proximity Read ↗

Association of the homeobox transcription factor gene ENGRAILED 2 with autistic disorder in Chinese children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.