Article
No association of polymorphisms in the CDK5, NDEL1, and LIS1 with autism in Chinese Han population.
Psychiatry research - 30 Dec 2011
Wang Lifang, Li Jun, Jia Meixiang, Yue Weihua, Ruan Yanyan, Lu Tianlan, Zhang Jishui, Liu Jing, Zhang Dai
Abstract excerpt
Autism is a pervasive neurodevelopmental disorder. CDK5 (cyclin-dependent kinase 5) and its interacting molecules are involved in neurodevelopment. We performed a family-based association analysis between CDK5, NDEL1, and LIS1 polymorphisms and autism in a Chinese Han population. Our study did not detect a significant association. It indicated that common genetic variations in these genes might not play a role in...
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