Article
The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.
European journal of human genetics : EJHG - 1 Feb 2009
Liu Xudong, Novosedlik Natalia, Wang Ami, Hudson Melissa L, Cohen Ira L, Chudley Albert E, Forster-Gibson Cynthia J, Lewis Suzanne M E, Holden Jeanette J A
Abstract excerpt
An imbalance between excitation and inhibition in the cerebral cortex has been suggested as a possible etiology of autism. The DLX genes encode homeodomain-containing transcription factors controlling the generation of GABAergic cortical interneurons. The DLX1 and DLX2 genes lie head-to-head in 2...
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