Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire

Abstract excerpt

Convergence of observations from different sources is the norm in science. However, when convergence occurs in man for antibodies it is remarkable because the repertoire of possible immunoglobulin products is very large and diverse. Thus, one would not expect to see the same antibody twice from divergent populations unless there is special significance as to why the immune response is constrained. Now, broadly...

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