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Article

Genetic association of sequence variants near AGER/NOTCH4 and dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Bennet Anna M, Reynolds Chandra A, Eriksson Ulrika K, Hong Mun-Gwan, Blennow Kaj, Gatz Margaret, Alexeyenko Andrey, Pedersen Nancy L, Prince Jonathan A

Abstract excerpt

We performed a survey of sequence variation in a series of 20 genes involved in inflammation-related pathways for association with dementia risk in twin and unrelated case-control samples consisting in total of 1462 Swedish dementia casesand 1929 controls. For a total of 218 tested genetic markers, strong evidence was obtained implicating a region near AGER and NOTCH4 on chromosome 6p with replication across both...

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Share to Chromosomes, Human, Pair 6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Receptor for Advanced Glycation End Products

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Source

Open in PubMed Open full text

Identifiers

PMID: 21297263
DOI: 10.3233/JAD-2011-101848
PMCID: PMC3477600

Genes

AGER
NOTCH4
APOE
CLU
PICALM
PSEN1
PSEN2

Provenance

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