Article
Multiple barriers to recombination between divergent HIV-1 variants revealed by a dual-marker recombination assay.
Journal of molecular biology - 8 Apr 2011
Nikolaitchik Olga A, Galli Andrea, Moore Michael D, Pathak Vinay K, Hu Wei-Shau
Abstract excerpt
Recombination is a major force for generating human immunodeficiency virus type 1 (HIV-1) diversity and produces numerous recombinants circulating in the human population. We previously established a cell-based system using green fluorescent protein gene (gfp) as a reporter to study the mechanisms of HIV-1 recombination. We now report an improved system capable of detecting recombination using authentic viral...
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