Article
Adaptive resistance to cationic compounds in Pseudomonas aeruginosa.
International journal of antimicrobial agents - 1 Mar 2011
Skiada Anna, Markogiannakis Antonis, Plachouras Diamantis, Daikos George L
Abstract excerpt
Adaptive resistance is an autoregulated phenomenon characterised by induction of resistance in the presence of drug and reversal to the sensitive phenotype in its absence. This type of resistance is well documented for polycationic antibiotics, including aminoglycosides and polymyxins, in Pseudomonas aeruginosa and other aerobic Gram-negative bacilli. It is not caused by selection of resistant mutants but rather...
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