Article
Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population.
Breast cancer research and treatment - 1 Jul 2011
Zhou Ping, Du Liang-Feng, Lv Guo-Qiang, Yu Xian-Ming, Gu Yuan-Long, Li Jian-Ping, Zhang Chun
Abstract excerpt
Activated Leukocyte Cell Adhesion Molecules (ALCAM, also called CD166, MEMD) are cell surface immunoglobulins that are considered to be prognostic markers for breast cancer. CD166/ALCAM has gained increasing attention because of its significant association with tumor progression and the metastatic spread of breast cancer. Two polymorphisms have been identified in the CD166/ALCAM gene: 5'UTR C/T (rs6437585) and...
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