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Article

CD166/activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion.

Neuro-oncology - 1 Oct 2012

Kijima Noriyuki, Hosen Naoki, Kagawa Naoki, Hashimoto Naoya, Nakano Akiko, Fujimoto Yasunori, Kinoshita Manabu, Sugiyama Haruo, Yoshimine Toshiki

Abstract excerpt

For improvement of prognosis for glioblastoma patients, which remains poor, identification and targeting of glioblastoma progenitor cells are crucial. In this study, we found that the cluster of differentiation (CD)166/activated leukocyte cell adhesion molecule (ALCAM) was highly expressed on CD133+ glioblastoma progenitor cells. ALCAM+ CD133+ cells were highly enriched with tumor sphere-initiating cells in...

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Identifiers

PMID: 22166264
DOI: 10.1093/neuonc/nor202
PMCID: PMC3452333

Genes

ALCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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