Article
Aspartokinase III repression and lysine analogs utilization for protein synthesis.
Physiological chemistry and physics and medical NMR - 1 Jan 1990
Di Girolamo M, Busiello V, Coccia R, Foppoli C
Abstract excerpt
The extents of thialysine and selenalysine incorporation into cell proteins were compared in E. coli KL16 and in a mutant able to grow equally well in the presence or in the absence of both lysine analogs. The mutant differs from the parental strain in the repression of aspartokinase III (AKIII), the first enzyme of the lysine biosynthetic pathway. No analog incorporation into proteins was observed in mutant...
Topics
- Aspartate Kinase
- Cysteine
- Enzyme Repression
- Escherichia coli
- Isoenzymes
- Lysine
- Mutation
- Organoselenium Compounds
- Protein Biosynthesis
- Selenium