Article
Predictive variables of sustained virological response after early discontinuation of triple therapy with telaprevir for genotype-1 HCV infection.
Gastroenterologia y hepatologia - 1 Jan 2000
Acero Fernández Doroteo, Morillas Cunill Rosa, Ferri Iglesias María José, Torras Collell Xavier, Vergara Gómez Mercedes, Zaragoza Velasco Natividad, López Nuñez Carmen, Forné Bardera Montserrat, Delgado Gómez Mercedes, Barenys Lacha Mercè, Torres Salinas Miquel, Villar Fernández Margarita, Durández Lázaro Rosa, Mariño Mendez Zoe
Abstract excerpt
BACKGROUND: Pivotal phase studies of telaprevir (TLV) and boceprevir (BOV) showed 10-56% rates of early treatment interruption. However, there have been no reports on the sustained virological response (SVR) rates of these patients. AIM: To assess the SVR rate in a large cohort of patients who discontinued triple therapy with TLV or BOV for reasons other than stopping rules and to identify variables predicting...
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