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Article

Deep sequencing reveals mixed infection with 2009 pandemic influenza A (H1N1) virus strains and the emergence of oseltamivir resistance.

The Journal of infectious diseases - 15 Jan 2011

Ghedin Elodie, Laplante Jennifer, DePasse Jay, Wentworth David E, Santos Roberto P, Lepow Martha L, Porter Joanne, Stellrecht Kathleen, Lin Xudong, Operario Darwin, Griesemer Sara, Fitch Adam, Halpin Rebecca A, Stockwell Timothy B, Spiro David J, Holmes Edward C, St George Kirsten

Abstract excerpt

Mixed infections with seasonal influenza A virus strains are a common occurrence and an important source of genetic diversity. Prolonged viral shedding, as observed in immunocompromised individuals, can lead to mutational accumulation over extended periods. Recently, drug resistance was reported in immunosuppressed patients infected with the 2009 pandemic influenza A (H1N1) virus within a few days after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21288815
DOI: 10.1093/infdis/jiq040
PMCID: PMC3071067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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