Article
Primarily oseltamivir-resistant influenza A (H1N1pdm09) virus evolving into a multidrug-resistant virus carrying H275Y and I223R neuraminidase substitutions.
Antiviral therapy - 1 Jan 2015
Grund Sebastian, Gkioule Charikleia, Termos Tahani, Pfeifer Nico, Kobbe Guido, Verheyen Jens, Adams Ortwin
Abstract excerpt
Antiviral susceptibility testing and reporting of viruses carrying amino acid substitutions conferring antiviral drug resistance is essential to assess the spread and clinical impact of these viruses. Here, we report on a patient who was infected with a primarily oseltamivir-resistant influenza A (H1N1pdm09) virus following allogeneic stem cell transplantation and rituximab treatment. Under prolonged virus...
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