Article
Vitamin D Receptor Gene Polymorphism: Association with Susceptibility to Early-Onset Breast Cancer in Iranian, BRCA1/2-Mutation Carrier and non-carrier Patients.
Pathology oncology research : POR - 1 Jul 2018
Shahabi Ahmad, Alipour Majid, Safiri Hamid, Tavakol Parsa, Alizadeh Mehdi, Milad Hashemi S, Shahabi Mahdieh, Halimi Mohammad
Abstract excerpt
Mounting evidences support that vitamin D insufficiency or deficiency is a risk factor of breast cancer. Vitamin D receptor (VDR) is expressed in more than 36 cell types in different organs as in cancerous cells. Numerous allelic variants of VDR gene have been identified in human populations. Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of...
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