Article
FokI polymorphism in vitamin D receptor gene and risk of breast cancer among Caucasian women.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2014
Shan Jin-lu, Dai Nan, Yang Xue-qin, Qian Cheng-yuan, Yang Zhen-zhou, Jin Feng, Li Mengxia, Wang Dong
Abstract excerpt
Vitamin D plays a central role in cellular proliferation, apoptosis induction, and tumor growth suppression. The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D. A series of epidemiological studies have examined the association between the VDR FokI polymorphism and breast cancer risk, but the findings remain inconclusive. Fifteen eligible case-control studies involving 15,681...
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