Article
Hornerin is a component of the epidermal cornified cell envelopes
31 Jan 2011
Abstract excerpt
ABSTRACT A single‐nucleotide polymorphism within the gene encoding hornerin (HRNR) has recently been linked with atopic dermatitis (AD) susceptibility. HRNR shares features with filaggrin, a key protein for keratino‐cyte differentiation, but conflicting reports have been published concerning its expression in the epidermis, and its role is still unknown. To analyze HRNR expression and function in the epidermis,...
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