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Article

Absence of the granular layer and keratohyalin define a morphologically distinct subset of individuals with ichthyosis vulgaris.

Experimental dermatology - 1 Aug 2002

Fleckman Philip, Brumbaugh Steven

Abstract excerpt

The clinical diagnosis of ichthyosis vulgaris (IV) can be difficult. Abnormalities in the granular layer and the ultrastructure of keratohyalin granules (KHG) suggest that morphology may be helpful. To clarify morphologic findings in IV, 41 clinically affected individuals and 21 unaffected family members or age- and sex-matched controls were studied by light microscopy. In these, the granular layer was totally...

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Identifiers

PMID: 12190941
DOI: 10.1034/j.1600-0625.2002.110406.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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