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Article

Impact of CYP19A1 genetic variations on polycystic ovary syndrome: findings from a case-control study.

F&S science - 1 Aug 2025

Chaudhary Hiral, Patel Jalpa, Jain Nayan K, Panchal Sonal, Nanavati Purvi, Singh Mala, Laddha Naresh, Joshi Rushikesh

Abstract excerpt

OBJECTIVE: To study the association between CYP19A1 genetic variants and the risk of developing polycystic ovary syndrome (PCOS). The study explored the relationship between the candidate gene CYP19A1 and hyperandrogenism, as well as its interplay with obesity, in PCOS patients compared with healthy controls. DESIGN: A case-control study with genetic association analysis by tetra-primer amplification refractory...

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Aromatase
Case-Control Studies
Gene Frequency
Genetic Association Studies
Hyperandrogenism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polycystic Ovary Syndrome

Polymerase Chain Reaction

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Identifiers

PMID: 40158801
DOI: 10.1016/j.xfss.2025.03.005

Genes

CYP19A1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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