Article
Alteration of REDD1-mediated mammalian target of rapamycin pathway and hypoxia-inducible factor-1α regulation in human breast cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2010
Koo Ja Seung, Jung Woohee
Abstract excerpt
OBJECTIVE: The purpose of this study is to investigate REDD1-(regulated in development and DNA damage response 1) mediated regulation of the mammalian target of rapamycin (mTOR) pathway in breast cancer. METHODS: A tissue microarray included samples from 224 patients with breast cancer, and 30 patients with papilloma were used as a control group. An immunohistochemistry (IHC) including estrogen receptor (ER),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
