Article
REDD1 and p-AKT over-expression may predict poor prognosis in ovarian cancer.
International journal of clinical and experimental pathology - 1 Jan 2014
Jia Wei, Chang Bin, Sun Lili, Zhu Huimin, Pang Lijuan, Tao Lin, Zou Hong, Du Jinze, Dong Yuling, Qi Yan, Jiang Jinfang, Liang Weihua, Li Feng, Zhao Xia
Abstract excerpt
We investigated the clinical significance of regulated in development and DNA damage response (REDD1) and p-AKT expression in human ovarian cancer (OC), explored the correlation of KRAS mutations with REDD1 expression, and assessed the therapeutic relevance of REDD1 in OC. We collected and immunohistochemically analyzed 118 formalin-fixed paraffin-embedded tumor tissue samples (100 primary OC and 18 borderline...
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