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Article

Association of endothelial nitric oxide synthase genotypes with bone mineral density, bone loss, hip structure, and risk of fracture in older women: the SOF study.

Bone - 1 Jul 2006

Taylor Brent C, Schreiner Pamela J, Zmuda Joseph M, Li Jia, Moffett Susan P, Beck Thomas J, Cummings Steven R, Lee Jocelyn M, Walker Karen, Ensrud Kristine E

Abstract excerpt

Nitric oxide (NO) is an important bone-signaling molecule. We examined the associations between the Glu298Asp polymorphism of NOS3, indices of bone strength, and the incidence of fracture among 6691 women aged 65 years and older enrolled in the Study of Osteoporotic Fractures. Calcaneal BMD was measured at an initial exam and after an average of 5.9 years of follow-up. Hip BMD was measured at an initial exam and...

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Source

Identifiers

PMID: 16503213
DOI: 10.1016/j.bone.2005.12.080

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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