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Article

Associations of APOE gene polymorphisms with bone mineral density and fracture risk: a meta-analysis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Apr 2011

Peter I, Crosier M D, Yoshida M, Booth S L, Cupples L A, Dawson-Hughes B, Karasik D, Kiel D P, Ordovas J M, Trikalinos T A

Abstract excerpt

UNLABELLED: To determine the association of the Apolipoprotein E (APOE) E4 gene polymorphism with bone mineral density (BMD) and fractures we conducted a meta-analysis of 17 reports. Despite lower trochanteric and lumbar BMD in APOE4 carriers, there is insufficient evidence to support a consistent association of APOE with bone health. INTRODUCTION: APOE has been studied for its potential role in osteoporosis...

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Identifiers

PMID: 20533025
DOI: 10.1007/s00198-010-1311-5
PMCID: PMC3144470

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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