Article
High-throughput genotyping of oncogenic human papilloma viruses with MALDI-TOF mass spectrometry.
Clinical chemistry - 1 Jan 2008
Söderlund-Strand Anna, Dillner Joakim, Carlson Joyce
Abstract excerpt
BACKGROUND: Human papilloma virus (HPV) is the major cause of cervical cancer. Use of HPV genotyping in cervical screening programs and for monitoring the effectiveness of HPV vaccination programs requires access to economical, high-throughput technology. METHODS: We used the Sequenom MassARRAY platform to develop a high-throughput mass spectrometric (MS) method for detecting 14 specific oncogenic HPV genotypes...
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