Article
Development of a fluorescence-based multiplex genotyping method for simultaneous determination of human papillomavirus infections and viral loads.
BMC cancer - 6 Nov 2015
Sun Zhengrong, Zhang Rong, Liu Zhonghua, Liu Chao, Li Xiulin, Zhou Weiqiang, Yang Lianxia, Ruan Qiang, Zhang Xu
Abstract excerpt
BACKGROUND: Persistent high-risk human papillomavirus (HPV) infection is correlated with an increased risk of developing intraepithelial lesion or malignancy (NILM). The aims of the current study is to establish a method named BioPerfectus Multiplex Real Time (BMRT) HPV assay for simultaneous typing and quantifying HPVs, and to evaluate it by comparison with HPV GenoArray test and PCR-sequencing method, as well...
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