Article
Development of a fluorescence-based multiplex genotyping method for simultaneous determination of human papillomavirus infections and viral loads.
BMC cancer - 6 Nov 2015
Sun Zhengrong, Zhang Rong, Liu Zhonghua, Liu Chao, Li Xiulin, Zhou Weiqiang, Yang Lianxia, Ruan Qiang, Zhang Xu
Abstract excerpt
BACKGROUND: Persistent high-risk human papillomavirus (HPV) infection is correlated with an increased risk of developing intraepithelial lesion or malignancy (NILM). The aims of the current study is to establish a method named BioPerfectus Multiplex Real Time (BMRT) HPV assay for simultaneous typ...
Topics
- Alphapapillomavirus
- Cervix Uteri
- DNA, Viral
- Female
- Genotype
- Human papillomavirus 16
- Human papillomavirus 18
- Humans
- Multiplex Polymerase Chain Reaction
- Papillomavirus Infections
- Real-Time Polymerase Chain Reaction
- Reproducibility of Results
- Sensitivity and Specificity