Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer.

Genetics and molecular research : GMR - 18 Jan 2011

Dodurga Y, Tataroglu C, Kesen Z, Satiroglu-Tufan N L

Abstract excerpt

Bladder cancer is the most frequent cancer of the urinary system. Fibroblast growth factor receptors (FGFR) belong to the tyrosine kinase family and have important roles in cell differentiation and proliferation and embryogenesis. FGFR3 is located on chromosome 4p16.3, and missense mutations of FGFR3 are associated with autosomal dominant human skeletal disorders and have some oncogenic effects. We examined the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Transitional Cell
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Neoplasm Staging

Share to Receptor, Fibroblast Growth Factor, Type 3

Share to Thanatophoric Dysplasia

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 21264819
DOI: 10.4238/vol10-1gmr923

Genes

FGFR3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Incidence of fibroblast growth factor receptor 3 gene (FGFR3) A248C, S249C, G372C, and T375C mutations in bladder cancer.PMID 21264819Read ↗

Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders.Semantic proximity Read ↗

Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours.Semantic proximity Read ↗

FGFR3 and TP53 mutation analysis in inverted urothelial papilloma: incidence and etiological considerations.Semantic proximity Read ↗

In-depth investigation of the molecular pathogenesis of bladder cancer in a unique 26-year old patient with extensive multifocal disease: a case report.Semantic proximity Read ↗

Frequency of activating mutations in FGFR2 exon 7 in bladder tumors from patients with early-onset and regular-onset disease.Semantic proximity Read ↗

The role of mutations and overexpression of the fibroblast growth factor receptor-3 in bladder cancer.Semantic proximity Read ↗

Frequent FGFR3 mutations in urothelial papillomaSemantic proximity Read ↗

FGFR3 and TP53 mutations in a prospective cohort of Belarusian bladder cancer patients.Semantic proximity Read ↗

Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors.Semantic proximity Read ↗

Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma.Semantic proximity Read ↗

Fibroblast growth factor receptor 3 gene (FGFR3) mutations in high-grade muscle-invasive urothelial bladder cancer in a Brazilian population: evaluation and prevalence.Semantic proximity Read ↗

APOBEC-mediated Mutagenesis as a Likely Cause of FGFR3 S249C Mutation Over-representation in Bladder CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.