Article
FGFR3 and TP53 mutation analysis in inverted urothelial papilloma: incidence and etiological considerations.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2009
Lott Sarah, Wang Mingsheng, Zhang Shaobo, MacLennan Gregory T, Lopez-Beltran Antonio, Montironi Rodolfo, Sung Ming-Tse, Tan Puay-Hoon, Cheng Liang
Abstract excerpt
Urothelial papillomas and low-grade urothelial carcinomas have shown a high incidence of fibroblast growth factor receptor 3 (FGFR3) mutations and are associated with a favorable prognosis. The association of FGFR3 mutations with inverted papillomas is less known. We analyzed 20 cases of inverted papilloma in the urinary tract. Mutations of FGFR3 (exons 7, 10, and 15) and TP53 genes were evaluated by DNA...
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