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Article

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.

PloS one - 14 Jan 2011

Strauss Robert, Li Zong-Yi, Liu Ying, Beyer Ines, Persson Jonas, Sova Pavel, Möller Thomas, Pesonen Sari, Hemminki Akseli, Hamerlik Petra, Drescher Charles, Urban Nicole, Bartek Jiri, Lieber André

Abstract excerpt

In our studies of ovarian cancer cells we have identified subpopulations of cells that are in a transitory E/M hybrid stage, i.e. cells that simultaneously express epithelial and mesenchymal markers. E/M cells are not homogenous but, in vitro and in vivo, contain subsets that can be distinguished based on a number of phenotypic features, including the subcellular localization of E-cadherin, and the expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Glandular and Epithelial

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Source

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Identifiers

PMID: 21264259
DOI: 10.1371/journal.pone.0016186
PMCID: PMC3021543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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