Article
Experimental selection of hypoxia-tolerant Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America - 8 Feb 2011
Zhou Dan, Udpa Nitin, Gersten Merril, Visk DeeAnn W, Bashir Ali, Xue Jin, Frazer Kelly A, Posakony James W, Subramaniam Shankar, Bafna Vineet, Haddad Gabriel G
Abstract excerpt
Through long-term laboratory selection (over 200 generations), we have generated Drosophila melanogaster populations that tolerate severe, normally lethal, levels of hypoxia. Because of initial experiments suspecting genetic mechanisms underlying this adaptation, we compared the genomes of the hy...
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