Article
Experimental selection for Drosophila survival in extremely low O(2) environment.
PloS one - 30 May 2007
Zhou Dan, Xue Jin, Chen Jianming, Morcillo Patrick, Lambert J David, White Kevin P, Haddad Gabriel G
Abstract excerpt
BACKGROUND: Cellular hypoxia, if severe enough, results usually in injury or cell death. Our research in this area has focused on the molecular mechanisms underlying hypoxic tissue injury to explore strategies to prevent injury or enhance tolerance. The current experiments were designed to determine the genetic basis for adaptation to long term low O(2) environments. METHODOLOGY/PRINCIPAL FINDINGS: With long term...
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