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Article

The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis.

PloS one - 1 Jan 2012

Sun Qiman, Song Kang, Shen Xizhong, Cai Yu

Abstract excerpt

BACKGROUND: KCNQ1 (potassium voltage-gated channel KQT-like sub-family, member 1) encodes a pore-forming subunit of a voltage-gated K(+) channel (KvLQT1) that plays a key role for the repolarization of the cardiac action potential as well as water and salt transport in epithelial tissues. Recently, genome-wide association studies have identified KCNQ1 as a type 2 diabetes (T2D) susceptibility gene in populations...

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Source

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Identifiers

PMID: 23133642
DOI: 10.1371/journal.pone.0048578
PMCID: PMC3487731

Genes

KCNQ1

Variants

Provenance

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The association between KCNQ1 gene polymorphism and type 2 diabetes risk: a meta-analysis.PMID 23133642Read ↗

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Common variants in KCNQ1 confer increased risk of type 2 diabetes and contribute to the diabetic epidemic in East Asians: a replication and meta-analysis.Semantic proximity Read ↗

KCNQ1 rs2237892 C→T gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 15,736 patients.Semantic proximity Read ↗

[Association of polymorphisms of potassium voltage-gated channel, KQT-like subfamily, member 1 and type 2 diabetes in Jiangsu province, China].Semantic proximity Read ↗

KCNQ1 rs2237895 gene polymorphism increases susceptibility to type 2 diabetes mellitus in Asian populationsSemantic proximity Read ↗

Risk of type 2 diabetes and KCNJ11 gene polymorphisms: a nested case–control study and meta-analysisSemantic proximity Read ↗

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