Article
Population specific impact of genetic variants in KCNJ11 gene to type 2 diabetes: a case-control and meta-analysis study.
PloS one - 1 Jan 2014
Phani Nagaraja M, Guddattu Vasudeva, Bellampalli Ravishankara, Seenappa Venu, Adhikari Prabha, Nagri Shivashankara K, D Souza Sydney C, Mundyat Gopinath P, Satyamoorthy Kapaettu, Rai Padmalatha S
Abstract excerpt
BACKGROUND AND OBJECTIVES: Potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) gene have a key role in insulin secretion and is of substantial interest as a candidate gene for type 2 diabetes (T2D). The current work was performed to delineate the genetic influence of KCNJ11 polymorphisms on risk of T2D in South Indian population through case-control association study along with systematic...
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