Article
Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes.
Molecular biology reports - 1 May 2013
Liu Jun, Wang Fang, Wu Yueyue, Huang Xinmei, Sheng Li, Xu Jiong, Zha Bingbing, Ding Heyuan, Chen Zaoping, Sun Tiange
Abstract excerpt
The potassium voltage-gated channel, KQT-like subfamily member 1 (KCNQ1) is a member of 11 mammalian Kv channel families that plays a key role for the repolarization of the cardiac action potential as well as water and salt transport. Genome-wide association studies have identified KCNQ1 as a type 2 diabetes (T2D) susceptibility gene in populations of Asian descent. After that, a number of studies reported that...
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