Article
Virulence of serotype M3 Group A Streptococcus strains in wax worms (Galleria mellonella larvae).
Virulence - 1 Jan 2000
Olsen Randall J, Watkins M Ebru, Cantu Concepcion C, Beres Stephen B, Musser James M
Abstract excerpt
Group A Streptococcus (GAS) causes human infections that range in severity from pharyngitis ("strep-throat") to necrotizing fasciitis ("flesh-eating disease"). To facilitate investigation of the molecular basis of host-pathogen interactions, infection models capable of rapidly screening for differences in GAS strain virulence are needed. To this end, we developed a Galleria mellonella larvae (wax worm) model of...
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