Article
Intermediate alleles at the FRAXA and FRAXE loci in Parkinson's disease.
Parkinsonism & related disorders - 1 May 2011
Costa Alzenira, Gao Lin, Carrillo Fátima, Cáceres-Redondo María Teresa, Carballo Manuel, Díaz-Martín Juan, Gómez-Garre Pilar, Sobrino Francisco, Lucas Miguel, López-Barneo José, Mir Pablo, Pintado Elizabeth
Abstract excerpt
BACKGROUND: It is debatable whether the size of triplet repeats of the fragile X mental retardation genes FMR1 and FMR2 (found at the FRAXA and FRAXE loci) is associated with Parkinson's disease (PD). The aims of the current study were to investigate the relationship between these genes and PD and to determine whether these genes affected clinical manifestations of PD. METHODS: We recruited 206 PD patients and...
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