Article
Screening for FMR1 expanded alleles in patients with parkinsonism in mainland China.
Neuroscience letters - 11 Apr 2012
Zhang Xiong, Zhuang Xiaosai, Gan Shirui, Wu Zhiying, Chen Wanjin, Hu Yanbing, Wang Ning
Abstract excerpt
Expanded alleles of the fragile X mental retardation 1 (FMR1) gene are generally divided into four classes based on the abundance of unstable CGG repeat expansions (CGGs) in its 5'-untranslated region. It has recently been reported that two of the four classes, premutation (55-200 CGGs) and gray zone (GZ, 40-54 CGGs) alleles, was potentially associated with parkinsonism. To investigate this association in...
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