Article
Screening for intermediate CGG alleles of FMR1 gene in male Iranian patients with Parkinsonism.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Jan 2017
Entezari Atefeh, Khaniani Mahmoud Shekari, Bahrami Tayyeb, Derakhshan Sima Mansoori, Darvish Hossein
Abstract excerpt
Male carriers of an expansion of CGG alleles (with 55-200 CGG repeats) in the FMR1 gene are affected with Fragile X-associated tremor/ataxia syndrome (FXTAS). On the other hand, individuals with Parkinson's disease (PD) or Parkinsonism spectrum disorders may have some clinical features that overlap with FXTAS. To investigate the possible association between PD and FMR1 expanded alleles, we screened a total of 154...
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