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Article

Evidence for the role of FMR1 gray zone alleles as a risk factor for parkinsonism in females.

Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2018

Loesch Danuta Z, Tassone Flora, Mellick George D, Horne Malcolm, Rubio Justin P, Bui Minh Q, Francis David, Storey Elsdon

Abstract excerpt

Background and Objective There is convincing evidence that small CGG expansion (41-54 repeats): FMR1 "gray zone" alleles (GZ) contribute to the risk of parkinsonism in males, but there is insufficient corresponding data in females. This study intends to fill this gap. Methods We screened whole-blood-derived DNA from a cohort of 601 females diagnosed with idiopathic PD, and from dry Guthrie blood spots from a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 30153395
DOI: 10.1002/mds.27420
PMCID: PMC6116531

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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