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Article

Frontotemporal lobar degeneration genome wide association study replication confirms a risk locus shared with amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Apr 2011

Rollinson Sara, Mead Simon, Snowden Julie, Richardson Anna, Rohrer Jonathan, Halliwell Nicola, Usher Suzanne, Neary David, Mann David, Hardy John, Pickering-Brown Stuart

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is a common cause of dementia especially in patients under the age of 65. FTLD has a high incidence of heritability with as many as 40% of patients reporting a family history of disease. Recently, the first genome wide association study was performed using only FTLD patients with a pathologically confirmed TDP-43 pathology. Genome wide significance was detected for a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21257233
DOI: 10.1016/j.neurobiolaging.2010.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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