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Article

Thermal denaturation of beta-galactosidase and of two site-specific mutants.

Biochemistry - 11 Dec 1990

Edwards R A, Jacobson A L, Huber R E

Abstract excerpt

The thermal denaturation of wild-type beta-galactosidase and two beta-galactosidases with substitutions at the active site was studied by kinetics, differential scanning calorimetry, electrophoresis, molecular exclusion chromatography, and circular dichroism. From the results, a model is developed for thermal denaturation of beta-galactosidase which includes the reversible dissociation of ligands, reversible...

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Identifiers

PMID: 2125499
DOI: 10.1021/bi00501a019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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