Article
Mitochondrial disorders in the nervous system.
Annual review of neuroscience - 1 Jan 2008
DiMauro Salvatore, Schon Eric A
Abstract excerpt
Mitochondrial diseases (encephalomyopathies) have traditionally been ascribed to defects of the respiratory chain, which has helped researchers explain their genetic and clinical complexity. However, other mitochondrial functions are greatly important for the nervous system, including protein importation, organellar dynamics, and programmed cell death. Defects in genes controlling these functions are attracting...
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