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Article

Sox3 Functions in a Cell-Autonomous Manner to Regulate Spermatogonial Differentiation in Mice

19 Jan 2011

Abstract excerpt

The X-linked Sox3 gene encodes a member of the Sry high-mobility group box proteins, which play a role in many developmental processes including neurogenesis and testis development. This study further examined the role of Sox3 in spermatogenesis. Males without Sox3 expression exhibited a similar number of germ cell nuclear antigen-positive germ cells at 1, 5, and 10 d postpartum (dpp) compared to their wild-type...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 21248142
DOI: 10.1210/en.2010-1249

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