Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.

Reproduction (Cambridge, England) - 1 Feb 2010

Yamaji Masashi, Tanaka Takashi, Shigeta Mayo, Chuma Shinichiro, Saga Yumiko, Saitou Mitinori

Abstract excerpt

Mutations of RNA-binding proteins such as NANOS3, TIAL1, and DND1 in mice have been known to result in the failure of survival and/or proliferation of primordial germ cells (PGCs) soon after their fate is specified (around embryonic day (E) 8.0), leading to the infertility of these animals. However, the mechanisms of actions of these RNA-binding proteins remain largely unresolved. As a foundation to explore the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Endoribonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eukaryotic Initiation Factor-2

Share to Gestational Age

Share to Infertility

Share to Ribonucleoproteins, Small Nuclear

Share to RNA Processing, Post-Transcriptional

Source

Identifiers

PMID: 19861488
DOI: 10.1530/REP-09-0373

Genes

NANOS3
TIAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3.PMID 19861488Read ↗

NANOS3 function in human germ cell developmentSemantic proximity Read ↗

Conserved role of nanos proteins in germ cell development.Semantic proximity Read ↗

The Role of Nanos in Germ Granules—Putative Posttranscriptional Regulation Hubs in Germ Cell Specification and Development Across SpeciesSemantic proximity Read ↗

A porcine germ cell depletion model to investigate the role of germ cells in gonadal developmentSemantic proximity Read ↗

A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells†.Semantic proximity Read ↗

Sexually Divergent Role of Germ Cells in Mammalian GonadogenesisSemantic proximity Read ↗

A male infertility mutation reverts NANOS1 activity from anti-apoptotic to pro-apoptotic by disrupting repression of <i>GADD45A</i> , <i>GADD45B</i> , <i>GADD45G</i> and <i>RHOB</i> genesSemantic proximity Read ↗

The piRNA protein Asz1 is essential for germ cell and gonad development in zebrafish and exhibits differential necessities in distinct types of RNP granulesSemantic proximity Read ↗

Sox3 Functions in a Cell-Autonomous Manner to Regulate Spermatogonial Differentiation in MiceSemantic proximity Read ↗

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.Semantic proximity Read ↗

nanos3 maintains germline stem cells and expression of the conserved germline stem cell gene nanos2 in the zebrafish ovary.Semantic proximity Read ↗

Maintaining sufficient nanos is a critical function for polar granule component in the specification of primordial germ cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.